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One Pfizer or Oxford Covid jab ‘significantly’ prevents hospitalisation in older people | Vaccines and immunisation

A single shot of the Pfizer/BioNTech or Oxford/AstraZeneca vaccine gives dramatic safety towards hospital admission and extreme illness in older individuals, in response to a brand new research from Public Well being England (PHE).

Matt Hancock hailed the real-world knowledge, which discovered both vaccine is greater than 80% efficient at stopping hospital admission round three to 4 weeks after the primary dose.

Professor Jonathan Van-Tam, England’s deputy chief medical officer, mentioned the information provided a glimpse of how the vaccine programme “goes to hopefully take us into a really completely different world within the subsequent few months”.

The research, which has but to be peer-reviewed, included greater than 7.5 million individuals aged 70 and over in England.

The info additionally reveals that infections (the place individuals show signs) within the over-70s fall from about three weeks after one dose of both vaccine.

Safety towards even growing symptomatic Covid-19 within the first place ranged between 57% and 61% for one dose of the Pfizer/BioNTech jab and between 60 and 73% for the Oxford/AstraZeneca vaccine, the research discovered.

On high of the safety towards symptomatic illness, individuals who had been vaccinated with one dose of the Pfizer vaccine had a further 43% decrease danger of emergency hospital admission and a further 51% decrease danger of dying, in response to the research.

In the meantime, individuals who had been vaccinated with one dose of the Oxford vaccine had a further 37% decrease danger of emergency hospital admission, whereas there’s presently inadequate follow-up knowledge to evaluate the impression on dying.

The authors mentioned each vaccines confirmed related results, including: “Mixed with the impact towards symptomatic illness, this means {that a} single dose of both vaccine is roughly 80% efficient at stopping hospitalisation and a single dose of [Pfizer] is 85% efficient at stopping dying with Covid-19.”

The well being secretary informed a Downing Road press convention the research was “extraordinarily excellent news”.

'Do not wreck this': Jonathan Van-Tam warns against breaking lockdown rules  – video
‘Don’t wreck this’: Jonathan Van-Tam warns towards breaking lockdown guidelines – video

Hancock mentioned: “In truth, the detailed knowledge present that the safety that you simply get from catching Covid 35 days after a primary jab is even barely higher for the Oxford jab than for Pfizer, albeit each outcomes are clearly very sturdy.”

The outcomes “can also assist to clarify why the variety of Covid admissions to intensive care items amongst individuals over 80 within the UK have dropped to single figures within the final couple of weeks”.

Van-Tam informed the briefing the information “offers us these first glimpses of how, if we’re affected person, and we give this vaccine programme time to have its full impact, it’ll hopefully take us into a really completely different world within the subsequent few months”.

Urging individuals to have their second doses, he mentioned: “I feel there’s fairly a big probability {that a} second dose of vaccine goes to mature your immune response, presumably make it broader and virtually definitely make it longer than it might in any other case be in relation to a primary dose solely.”

That meant it was completely essential that second doses “are nonetheless a part of the course of immunisation towards Covid-19 and no much less necessary for that cause”.

Dr Mary Ramsay, PHE head of immunisation, mentioned of the research: “This provides to rising proof displaying that the vaccines are working to cut back infections and save lives. Whereas there stays far more knowledge to observe, that is encouraging and we’re more and more assured that vaccines are making an actual distinction.

“It is very important do not forget that safety is just not full and we don’t but understand how a lot these vaccines will scale back the chance of you passing Covid-19 on to others. Even when you have been vaccinated, it’s actually necessary that you simply proceed to behave like you will have the virus, practise good hand hygiene and keep at house.”

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